Mikhail Blagosklonny: The great uses of Rapamycin

Mikhail Blagosklonny is a scientist who is currently working for Roswell Park Cancer Institute. Mikhail has been serving in this institution for a while now, and he is believed to have introduced several changes. The institute is based in Buffalo, New York City.While working in the organization, Mikhail has been in charge of several research projects, especially those concerning cancer and aging. Apart from being a professor of oncology at the well-known institution, Mikhail is the chief editor for one of the most popular scientific journals in the United States, known as Oncotarget. While serving in this position, the scientist has done a lot to help people to understand cancer and its treatments. Under his leadership, the successful journal has published several cancer studies, and they have assisted very many individuals in the world.

Mikhail Blagosklonny has been instrumental in the invention of a drug known as Rapamycin. The medical drug is also called Sirolimus, and it is mostly used by medical professionals in the world to prevent any organ transplant rejection by the human body. In the past, the drug has also been used to treat coronary stents and several lung diseases. In the market, the drug is called Rapamune. Some people say that the drug helped them to cure several types of cancer. According to Mikhail Blagosklonny, the cancer drug was first discovered in the year 1972 on Easter Island. The people who discovered it used it as a very effective anti-fungal agent. Later on, medical professionals realized that the drug had wonderful antiproliferative properties and immunosuppressive features. When medical professionals made this discovery, they chose to abandon the use of the great medical drug as an anti-fungal agent. While serving at the Roswell Park Cancer Institute, Mikhail has been a staunch supporter for the use of Rapamycin. The scientist says that the drug is very effective for the treatment of cancer and increasing the lifespan of humans.

According to Blagosklonny, individuals who use the drug tend to live longer when compared to the ones who do not.For the individuals living with the hemolytic –uremic syndrome, a great medical professionals say that they are likely to get the help they have been searching when they use Rapamycin. The medical condition is very rare, and it is mostly caused by kidney failure, anemia and low platelet count in the body. When a patient has this condition, they get a major renal failure, and they do not get the treatment they need in a short time, they get serious problems. These patients are sometimes forced to undergo a permanent dialysis so that they might prolong their lives. If you are suffering from this condition, the only permanent solution is getting kidney transplantation. Sometimes, the new kidney can contract the same disease, and this is why most patients will be advised to use Rapamycin. According to Mikhail Blagosklonny, the drug has very little toxicity to the human kidneys, and it is the best remedy to kidney transplant patients. Mikhail says that the people using the drug have a high probability of living a better life.

The importance of attending Wessex Institute of Technology

Wessex Institute is a renowned research institution which is found in England. The center facilitates active research in various fields which include mechanics, environmental, ecology, damage, and fracture among others. The postgraduate programs are offered to sharpen the learners and equip them with skills that are desirable by employers in the job market. Learners have an opportunity for career development with all resources provided.

Type of courses offered

Courses offered Wessex Institute of Technology offers undergraduate, postgraduate, and short courses programs. The courses are well developed to equip the learner with appropriate technical and academic skills. Provision of short courses that are industry and academic based. Graduates from the institution are all-round figures and can fit in the job market.

Listing of vacancies

Career opportunities are available in plenty for those with certificates on these programs. When opportunities are available in the institution, the positions are listed for applicants and graduates from the school are given an upper hand.

James Dondero Defines Success

James Dondero is someone who is a leader in exhibiting success. This leadership is why Mr. Dondero is managing over 21 billion dollars as portfolio manager for Highland Capital Management. It is also the reason why he is sought after and serves as a board member and advisor of other firms as diverse as Cornerstone Healthcare and MGM Studios.
Mr. Dondero began his career in the field in which he has excelled. After obtaining degrees from the University of Virginia and McIntire School of Commerce, Mr. Dondero commenced working with Morgan Guaranty Trust Company where he completed their financial training program. In 1985 he commenced working with American Express where he managed a fixed income investment portfolio of over one billion dollars. He followed this success at Protective Life’s GIC subsidiary where he took the program from being just a concept in 1989 to over 2 billion dollars in assets by 1993. This was followed by similar tenures at NexBank and Cornerstone Healthcare Group Holdings. He continues to serve as Chairman of the Board and director at each of these companies.
Where Mr. Dondero of jimdondero.com has shone brightest is in the development of Collateralized Loan Obligations (CLO’s). Helping to lead the way in developing these securities has made Mr. Dondero a true leader in high return investments while mitigating the risks. By taking a pool of loans which are low rated and grouping them together, the investor reaps the benefit of the higher interest rate return while spreading the risk of default among a number of different borrowers. This has provided a much needed source of capital for business while not putting the investor at the same level of risk as a single lower rated bond.
While Mr. Dondero has achieved great success in the world of finance, he is passionate in philanthropy pursuits. He led HCM to issue the $1 Million Challenge Grant program which is raising money for Snowball Express. Snowball Express assists children of fallen veterans. The Challenge has been successful in getting funds raised, including a recent $70,000.00 grant from the Gary Sinise Foundation. Mr. Dondero believes in giving back to those who have given so much to this country.
In addition to veteran’s issues, Mr. Dondero gives extensively to programs to enhance excellence in education. One such outlet for Mr. Dondero’s donations in support of education has been through the Santa Barbara Foundation which recently issued almost $700,000.00 in grants to 17 non-profit groups supporting excellence in education. Mr. Dondero selected the Santa Barbara Foundation as a vehicle for HCM’s donations due to the quality of their community outreach programs.
James Dondero defines success. His career is a blueprint for success. Learn, work hard and seek out innovation is one half of success. The other half is giving unselfishly to community and country. Applying this balance is why Mr. Dondero enjoys real success in business and in life.