The contributions of Mikhael Blogosklonny to cancer and antiaging research.

Mikhael Blogosklonny is a well-known scientist who has dedicated his life to studying cancer and aging. He attained his Ph.D. in experimental medicine and cardiology as well as his M.D in internal medicine from St. Peterburg medical University and is now working at Roswell Park Institute as a professor of Oncology where he is able to carry out his research.Blogosklonny is also a well know philanthropist by his own right this is because of his altruistic aim in life to ensure that all people globally are accorded the finest treatment regardless of their financial status.The ability to reduce or even halt the process of aging has always been at the back of many scientists’ minds for many years now. The research on anti aging started way back in 1972 under a scientist by the name Suren Sehgal who had discovered a bacterium Streptomyces hygroscopicus which became the foundation for the anti-aging drug research. He is credited with discovering rapamycin a potent compound secreted by the bacteria which had antifungal properties.

Segal had found out that the antifungal properties of rapamycin could be used to cure skin disease and had used it on one of his neighbors with great results. In addition to this antifungal property, he had also discovered that it could also be used to suppress the immune system and was more applicable during organ transplants. As a result of this breakthrough discovery, the FDA quickly approved rapamycin for its use, particularly in organ transplant procedures. Unfortunately, Segal had passed away just a few years before finally witnessing how his discovery had gone on to save the lives of so many people undergoing organ transplants in the world.Blogosklonny specific area of research work has been based on finding a cure for cancer and the science behind aging. One of his major findings was the use of rapamycin as a cancer drug and its potential to prolong life. This great breakthrough was however not received well and received lots of critique by other scientists.

A few years later it was backed up by the National Institute Health (NIH) scientists in a huge study they had funded which proved Blogosklonny findings to be accurate and correct. The NIH scientists carried out experiments on mice by administering rapamycin and found out that the mice life was increased by a margin of thirteen percent in females and nine percent in male mice, making a conclusion that the lead drug prolonged life and reduced tumor growth. This could be equated to having the life span of a 65-year-old person being extended to 95 years. However, this was disputed because rapamycin had the effects of lowering a persons’ immunity and could not be administered to the old who already have weak immune systems.A few years down the line (2014) his life’s work started gaining recognition as a result of the Science family journal publishing new discoveries supporting his own findings. The new discoveries had also stipulated that a derivative of rapamycin- evelrolimus was boosting immunity when administered in low doses thus making it applicable as an anti-aging drug.